Evaluation of the Effects of Ultra-Low Dose Naloxone on Brachial Plexus Block with Bupivacaine

Introduction: Adjuvants are used in conjunction with local anaesthetics for brachial plexus block to quicken onset, prolong duration and augment the quality of anaesthesia.
 Objectives: The study aims evaluate effect adding ultra-low dose naloxone bupivacaine on postoperative analgesia.
 Methodology: A prospective, randomized, double-blind was conducted including forty American Society Anesthesiologists Physical Status (ASA PS) I II patients either sex between 15 65 years age scheduled upper limb surgery. They were randomized into two groups. Group BN received a mixture 0.33% plain (100 ng) group BS saline. procedure standardized both onset sensory motor assessed pinprick sensation muscle power respectively. Visual Analogue Score (VAS) assess pain at 1, 2, 4, 8 12 hours postoperatively.
 Result: comparable respect age, sex, ASA PS, baseline hemodynamic respiratory parameters mean analgesia significantly longer (610.7±125.4 mins) as compared (354.3±59.6 (p<0.001). No complications noted groups.
 Conclusion: This demonstrated that 100 ng naloxone, when supraclavicular block, prolongs after surgeries, without any significant side effects.